CAHYAWATI, PUTU NITA (2020) Simvastatin Improves Renal Function and Glomerulosclerosis in Ischemic-reperfusion Injury. Indones Biomed.
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TURNITIN_Simvastatin improves renal function and glomerulosclerosis in ischemic-reperfusion injury, (1).pdf Download (2MB) | Preview |
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Abstract
Eighteen male Swiss mice were grouped into sham operation group (GSO), I/R injury group (GIRI), and simvastatin group (GSIM). The GSO group was performed by sham operation and pretreatment of 1% carboxymethylcellulose (CMC) for 3 days. The GIRI group was performed by I/R procedure and pretreatment of 1% CMC for 3 days and the GSIM group was performed by I/R procedure and pretreatment of 10 mg/kg BW simvastatin for 3 days. Blood urea nitrogen (BUN) and creatinine serum were assessed to determine kidney function. Histopathological analysis of glomerulosclerosis was assessed by the extent of glomerular damage (sclerosis), capillary loops, and synechia. The data were analyzed by one-way ANOVA followed by post hoc Tukey’s test (p<0.05).
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Institution of Research and Community Service (LP2M) > Medical Education |
| Depositing User: | I Putu Astina |
| Date Deposited: | 05 Mar 2024 07:10 |
| Last Modified: | 05 Mar 2024 07:10 |
| URI: | http://repository.warmadewa.ac.id/id/eprint/2462 |
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